All Phenotypes Wbp1l<tm2c(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Wbp1l^{tm2c(EUCOMM)Hmgu}
targeted mutation 2c, Helmholtz Zentrum Muenchen GmbH
MGI:6458551

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Wbp1l^{tm2c(EUCOMM)Hmgu}/Wbp1l^{tm2c(EUCOMM)Hmgu} Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺	involves: 129S4/SvJae * C57BL/6N * SJL	MGI:6458733

Allelic Composition	Wbp1l^{tm2c(EUCOMM)Hmgu}/Wbp1l^{tm2c(EUCOMM)Hmgu} Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺
Genetic Background	involves: 129S4/SvJae * C57BL/6N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj} mutation (3 available); any Gt(ROSA)26Sor mutation (993 available)
Wbp1l^{tm2c(EUCOMM)Hmgu} mutation (0 available); any Wbp1l mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal bone marrow cell physiology ( J:284781 )

• tamoxifen-treated KIT+ bone marrow cells exhibit increased migration in a transwell assay in vitro and increased bone marrow homing in vivo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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