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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Fmo3em1Jmbn
endonuclease-mediated mutation 1, J Mark Brown
MGI:6458889
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Fmo3em1Jmbn/Fmo3em1Jmbn C57BL/6-Fmo3em1Jmbn MGI:6458893
cx2
Fmo3em1Jmbn/Fmo3em1Jmbn
Ldlrtm1Her/Ldlrtm1Her
involves: 129S7/SvEvBrd * C57BL/6 MGI:6458894


Genotype
MGI:6458893
hm1
Allelic
Composition
Fmo3em1Jmbn/Fmo3em1Jmbn
Genetic
Background
C57BL/6-Fmo3em1Jmbn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fmo3em1Jmbn mutation (0 available); any Fmo3 mutation (40 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• under non-obesogenic conditions




Genotype
MGI:6458894
cx2
Allelic
Composition
Fmo3em1Jmbn/Fmo3em1Jmbn
Ldlrtm1Her/Ldlrtm1Her
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fmo3em1Jmbn mutation (0 available); any Fmo3 mutation (40 available)
Ldlrtm1Her mutation (19 available); any Ldlr mutation (81 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• compared with control mice when fed a Western diet
• when fed a Western diet, mice exhibit increased expression of brown/beige adipocyte markers in subcutaneous fat depots compared with control mice

growth/size/body
• when fed a Western diet, mice exhibit reduced body weight and body fat compared with control mice

homeostasis/metabolism
• when fed a Western diet, mice exhibit reduced body weight and body fat compared with control mice





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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory