About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nfil3tm1.2Kubo
targeted mutation 1.2, Masato Kubo
MGI:6460440
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Commd10Tg(Vav1-icre)A2Kio/0
Nfil3tm1.2Kubo/Nfil3tm1.2Kubo 		involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca MGI:7448515
cn2
 		Nfil3tm1.2Kubo/Nfil3tm1.2Kubo
Tg(Itgax-cre)1-1Reiz/0 		involves: 129 * C57BL/6 * CBA MGI:7448516


Genotype
MGI:7448515
cn1
Allelic
Composition		 Commd10Tg(Vav1-icre)A2Kio/0
Nfil3tm1.2Kubo/Nfil3tm1.2Kubo
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Commd10Tg(Vav1-icre)A2Kio mutation (3 available); any Commd10 mutation (24 available)
Nfil3tm1.2Kubo mutation (0 available); any Nfil3 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased dendritic cell number ( J:334296 )
• cDC1s virtually absent

immune system
decreased dendritic cell number ( J:334296 )
• cDC1s virtually absent




Genotype
MGI:7448516
cn2
Allelic
Composition		 Nfil3tm1.2Kubo/Nfil3tm1.2Kubo
Tg(Itgax-cre)1-1Reiz/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfil3tm1.2Kubo mutation (0 available); any Nfil3 mutation (32 available)
Tg(Itgax-cre)1-1Reiz mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:334296 )
N
• normal cDC1 development

immune system
immune system phenotype ( J:334296 )
N
• normal cDC1 development




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory