reproductive system
N |
• female mice without hydrocephalus exhibit normal fertility
|
• abnormal radial spokes
|
nervous system
hydrocephaly
(
J:293391
)
• at P1 and P6
|
• at P6
|
• fused
|
• at P6 in the mid-sagittal despite normal ependymal cilia generated flow
|
respiratory system
• accumulation of mucus despite normal cilia length
|
• increased ciliary beat frequency of tracheal explants multiciliated cells from 10 weeks to 3 months old mice
|
skeleton
• beginning at 2 to 3 weeks after birth in most mice
|
growth/size/body
• accumulation of mucus despite normal cilia length
|
embryo
N |
• mice exhibit normal left-right asymmetry
|
craniofacial
• beginning at 2 to 3 weeks after birth in most mice
|
• accumulation of mucus despite normal cilia length
|
cellular
• abnormal radial spokes
|