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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cfap206tm1.2Gos
targeted mutation 1.2, Achim Gossler
MGI:6466698
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cfap206tm1.2Gos/Cfap206tm1.2Gos involves: 129 * C57BL/6J * CD-1 * SJL MGI:6466705


Genotype
MGI:6466705
hm1
Allelic
Composition
Cfap206tm1.2Gos/Cfap206tm1.2Gos
Genetic
Background
involves: 129 * C57BL/6J * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cfap206tm1.2Gos mutation (1 available); any Cfap206 mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• female mice without hydrocephalus exhibit normal fertility
• abnormal radial spokes

nervous system
• at P1 and P6
• at P6 in the mid-sagittal despite normal ependymal cilia generated flow

respiratory system
• accumulation of mucus despite normal cilia length
• increased ciliary beat frequency of tracheal explants multiciliated cells from 10 weeks to 3 months old mice

skeleton
• beginning at 2 to 3 weeks after birth in most mice

growth/size/body
• accumulation of mucus despite normal cilia length

embryo
N
• mice exhibit normal left-right asymmetry

craniofacial
• beginning at 2 to 3 weeks after birth in most mice
• accumulation of mucus despite normal cilia length

cellular
• abnormal radial spokes





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory