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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc6a3tm1c(KOMP)Wtsi
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:6467307
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Aldh1a1tm1.1(cre/ERT2)Cai/Aldh1a1+
Slc6a3tm1c(KOMP)Wtsi/Slc6a3tm1c(KOMP)Wtsi 		involves: C57BL/6N * SJL MGI:6467328


Genotype
MGI:6467328
cn1
Allelic
Composition		 Aldh1a1tm1.1(cre/ERT2)Cai/Aldh1a1+
Slc6a3tm1c(KOMP)Wtsi/Slc6a3tm1c(KOMP)Wtsi
Genetic
Background		 involves: C57BL/6N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aldh1a1tm1.1(cre/ERT2)Cai mutation (0 available); any Aldh1a1 mutation (39 available)
Slc6a3tm1c(KOMP)Wtsi mutation (0 available); any Slc6a3 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:280705 )
N
• mice exhibit normal anxiety-like responses
abnormal motor coordination/balance ( J:280705 )
• tamoxifen-treated mice exhibit less frequent higher-speed walking compared with wild-type mice
• however, mice exhibit normal frequency of lower-speed walking, stride length, and stance and swing time




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory