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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc25a11em1Syki
endonuclease-mediated mutation 1, Soo-Youl Kim
MGI:6469639
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc25a11em1Syki/Slc25a11em1Syki Not Specified MGI:6469641
cx2
 		Slc25a11em1Syki/Slc25a11+
Krastm3Tyj/Kras+ 		involves: 129S * C57BL/6 MGI:6469642


Genotype
MGI:6469641
hm1
Allelic
Composition		 Slc25a11em1Syki/Slc25a11em1Syki
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a11em1Syki mutation (0 available); any Slc25a11 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6469642
cx2
Allelic
Composition		 Slc25a11em1Syki/Slc25a11+
Krastm3Tyj/Kras+
Genetic
Background		 involves: 129S * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm3Tyj mutation (2 available); any Kras mutation (84 available)
Slc25a11em1Syki mutation (0 available); any Slc25a11 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased lung tumor incidence ( J:294965 )
• 60% reduction of number of tumor nodes at age 12 weeks
• 54% reduction in tumor area at age 12 weeks

respiratory system
decreased lung tumor incidence ( J:294965 )
• 60% reduction of number of tumor nodes at age 12 weeks
• 54% reduction in tumor area at age 12 weeks




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory