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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc16a3tm1.1Lupel
targeted mutation 1.1, Luc Pellerin
MGI:6471733
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Slc16a3tm1.1Lupel/Slc16a3tm1.1Lupel C57BL/6J-Slc16a3tm1.1Lupel MGI:6473221


Genotype
MGI:6473221
cn1
Allelic
Composition
Slc16a3tm1.1Lupel/Slc16a3tm1.1Lupel
Genetic
Background
C57BL/6J-Slc16a3tm1.1Lupel
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc16a3tm1.1Lupel mutation (0 available); any Slc16a3 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• normal novel object recognition 90 minutes after introduction to novel object in mice with dorsal hippocampal astrocyte-specific knock-out
• normal recall 7 days after Morris water maze test in mice with dorsal hippocampal astrocyte-specific knock-out
• normal mobility and thigmotaxis in open field test introduction in mice with dorsal hippocampal astrocyte-specific knock-out
• normal behavior in predator odor test and elevated plus-maze and Y-maze tests in mice with dorsal hippocampal astrocyte-specific knock-out
• normal time scores for immobility, swimming and climbing in forced swimming test in mice with dorsal hippocampal astrocyte-specific knock-out
• impaired novel object recognition 24 hrs after introduction in mice with dorsal hippocampal astrocyte-specific knock-out
• normal novel object recognition 90 minutes after introduction in mice with dorsal hippocampal astrocyte-specific knock-out
• impaired novel object recognition 24 hrs after introduction in mice with dorsal hippocampal astrocyte-specific knock-out
• delay in time to find platform on day 2 of Morris water maze test in mice with dorsal hippocampal astrocyte-specific knock-out
• normal time to find platform on days 3-6 of Morris water maze test in mice with dorsal hippocampal astrocyte-specific knock-out

nervous system
N
• normal argyrophilic areas in the dentate gyrus in mice with dorsal hippocampal astrocyte-specific knock-out





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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory