Phenotypes associated with this allele

• Allele Symbol: Prkd3^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6472607
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkd3^tm1b(EUCOMM)Wtsi/Prkd3^tm1b(EUCOMM)Wtsi	C57BL/6N-Prkd3^tm1b(EUCOMM)Wtsi/Ieg	MGI:6696871
ht2	Prkd3^tm1b(EUCOMM)Wtsi/Prkd3^+	C57BL/6N-Prkd3^tm1b(EUCOMM)Wtsi/Ieg	MGI:6696870

Genotype
MGI:6696871

hm1

• Allelic Composition: Prkd3^{tm1b(EUCOMM)Wtsi}/Prkd3^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Prkd3^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0456_4_H05

Data Sources

IMPC Data for Prkd3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6696870

ht2

• Allelic Composition: Prkd3^{tm1b(EUCOMM)Wtsi}/Prkd3⁺
• Genetic Background: C57BL/6N-Prkd3^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0456_4_H05

Data Sources

IMPC Data for Prkd3

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HMGU

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

IMPC - HMGU

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - HMGU

increased circulating aspartate transaminase level ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HMGU

decreased total retina thickness ( J:211773 )

IMPC - HMGU