Phenotypes associated with this allele

• Allele Symbol: Lrrc55os^em1Caox
• Allele Name: endonuclease-mediated mutation 1, Xuetao Cao
• Allele ID: MGI:6477292
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrrc55os^em1Caox/Lrrc55os^em1Caox	C57BL/6-Lrrc55os^em1Caox	MGI:6477305

Genotype
MGI:6477305

hm1

• Allelic Composition: Lrrc55os^em1Caox/Lrrc55os^em1Caox
• Genetic Background: C57BL/6-Lrrc55os^em1Caox

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:293325 )

N • normal CD4+ CD8+ T cell, B cell and neutrophil population distribution in spleen

decreased circulating interferon-beta level ( J:293325 )

• 12 h after vesicular stomatitis virus (VSV) infection

increased susceptibility to Riboviria infection ( J:293325 )

• increased virus titers when infected with vesicular stomatitis virus (VSV)

• increased viral replication when infected with VSV

• increased inflammatory cell infiltration of organs when infected with VSV

increased susceptibility to Riboviria infection induced morbidity/mortality ( J:293325 )

• lower survival rate when infected with VSV

mortality/aging

increased susceptibility to Riboviria infection induced morbidity/mortality ( J:293325 )

• lower survival rate when infected with VSV

homeostasis/metabolism

decreased circulating interferon-beta level ( J:293325 )

• 12 h after vesicular stomatitis virus (VSV) infection

behavior/neurological

behavior/neurological phenotype ( J:293325 )

N • normal behavior

growth/size/body

growth/size/body region phenotype ( J:293325 )

N • normal development