Phenotypes associated with this allele

• Allele Symbol: Tmem126b^em1Cya
• Allele Name: endonuclease-mediated mutation 1, Cyagen Biosciences
• Allele ID: MGI:6478924
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem126b^em1Cya/Tmem126b^em1Cya	involves: C57BL/6J	MGI:6479041

Genotype
MGI:6479041

hm1

• Allelic Composition: Tmem126b^em1Cya/Tmem126b^em1Cya
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to induced morbidity/mortality ( J:291866 )

• reduced high-fat diet-induced serum and kidney triglyceride and total cholesterol level and fasting glucose and insulin level rise

• reduced high-fat diet-induced insulin resistance

• reduced high-fat diet-induced apoptosis in kidney

• reduced high-fat diet-induced inflammation, oxidative stress and mitochondrial dysfunction in kidney

• reduced high-fat diet-induced dyslipidemia

homeostasis/metabolism

decreased susceptibility to diet-induced obesity ( J:291866 )

• reduced high-fat diet-induced body weight gain

growth/size/body

decreased susceptibility to diet-induced obesity ( J:291866 )

• reduced high-fat diet-induced body weight gain