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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ppp1r14aem2Gpt
endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
MGI:6487903
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ppp1r14aem2Gpt/Ppp1r14aem2Gpt involves: C57BL/6J MGI:6487907


Genotype
MGI:6487907
hm1
Allelic
Composition
Ppp1r14aem2Gpt/Ppp1r14aem2Gpt
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp1r14aem2Gpt mutation (0 available); any Ppp1r14a mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• on a high fat diet, obese mice fail to show an increase in systolic blood pressure compared to normal chow fed mutant controls, unlike wild-type mice where most obese mice showed an increase in blood pressure compared to normal diet wild-type controls
• on a normal chow diet, blood pressure is similar to wild-type controls
• weight gain on a high fat diet is similar to diet matched wild-type controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory