About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ubr5em1Mem
endonuclease-mediated mutation 1, Marcy E MacDonald
MGI:6489293
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ubr5em1Mem/Ubr5em1Mem C57BL/6J-Ubr5em1Mem MGI:6489873
cx2
Htttm5Mem/Htt+
Ubr5em1Mem/Ubr5+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:6489874


Genotype
MGI:6489873
hm1
Allelic
Composition
Ubr5em1Mem/Ubr5em1Mem
Genetic
Background
C57BL/6J-Ubr5em1Mem
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ubr5em1Mem mutation (0 available); any Ubr5 mutation (117 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are present at weaning




Genotype
MGI:6489874
cx2
Allelic
Composition
Htttm5Mem/Htt+
Ubr5em1Mem/Ubr5+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htttm5Mem mutation (2 available); any Htt mutation (178 available)
Ubr5em1Mem mutation (0 available); any Ubr5 mutation (117 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• expansion of the Htt CAG triplet repeats in striatum and liver at 5 months of age





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory