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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mmachcem1.1Poche
endonuclease-mediated mutation 1.1, Ross Poche
MGI:6491443
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mmachcem1.1Poche/Mmachcem1.1Poche involves: C57BL/6J * FVB/N MGI:6491473


Genotype
MGI:6491473
hm1
Allelic
Composition
Mmachcem1.1Poche/Mmachcem1.1Poche
Genetic
Background
involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmachcem1.1Poche mutation (0 available); any Mmachc mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• Mendelian ratios of embryos are seen at E9.5 but only 3.6% at E15, indicating that mutants die between E9.5 and E15.5

growth/size/body
• E15.5 mutant is smaller

embryo
• E9.5 embryos have heartbeats but have yet to undergo turning

cardiovascular system
• E15.5 mutant shows right ventricular hypoplasia

craniofacial
• E15.5 mutant exhibits craniofacial dysmorphia

vision/eye
• E15.5 mutant is anophthalmic





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory