Phenotypes associated with this allele

• Allele Symbol: Tubb2a^em2Rstot
• Allele Name: endonuclease-mediated mutation 2, Rolf Stottmann
• Allele ID: MGI:6506265
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tubb2a^em2Rstot/Tubb2a^em2Rstot	involves: C57BL/6J * C57BL/6N	MGI:6507149

Genotype
MGI:6507149

hm1

• Allelic Composition: Tubb2a^em2Rstot/Tubb2a^em2Rstot
• Genetic Background: involves: C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal cerebral cortex morphology ( J:278765 )

• differentiated neurons appear to be more dispersed and there is a subtle increase in the proportion of CTIP2- positive cells in the middle third of the cortex at the expense of the dorsal third

abnormal primary motor cortex morphology ( J:278765 )

• slight decrease in the number of cells in the motor cortex

abnormal somatosensory cortex morphology ( J:278765 )

• slight decrease in the number of cells in the somatosensory cortex

abnormal axon morphology ( J:278765 )

• decrease in axonal staining in the corpus callosum and pyramidal fibers