Analysis Tools
behavior/neurological
| N |
• normal response to key jangling and normal whisker touch and ear twitch reflex
• normal pain sensitivity in hot plate test
• normal behavior in Porsolt forced swimming, elevated plus maze and Barnes maze tests
• normal posture and righting reflex
• normal latency to fall in wire hang test
• normal coordination in rotarod test
• normal behavior in tail suspension test
• normal behavior in social interaction test
|
|
• normal behavior in cued fear extinction test
• lower levels of freezing in cued fear conditioning test (acoustic stimulus + foot shock)
• normal behavior in cued test 35 days after conditioning in cued fear conditioning test (acoustic stimulus + foot shock)
|
|
• increased correct choice in spontaneous alternation and left-right discrimination T-maze tests
|
|
• reduced time spent in center in open field test
|
|
• significantly reduced acoustic startle reflex
|
|
• in open field test
|
|
• reduced locomotor activity: decrease in total distance traveled in light and dark chambers and decrease in number of transitions in light/dark transition test
• reduced locomotor activity: decrease in total distance traveled in open field test
• lower locomotor activity in home cage social activity test
• normal time spent in light chamber and normal latency to first transition
|
|
• reduced stereotypic counts in open field test
|
|
• less time spent apart in home cage social activity test
|
|
• more time spent with cage with unfamiliar mouse than with empty cage in sociability test
|
|
• less time spent with novel mouse in social novelty preference test: equal time spent with familiar and unfamiliar mouse
|
growth/size/body
homeostasis/metabolism
| N |
• normal body temperature
|
integument
| N |
• normal fur and whiskers
|
nervous system
|
• in acoustic startle reflex test
|
