Analysis Tools
behavior/neurological
| N |
• normal response to key jangling and normal whisker touch and ear twitch reflex
• normal pain sensitivity in hot plate test
• normal behavior in Porsolt forced swimming, elevated plus maze and Barnes maze tests
• normal posture and righting reflex
• normal latency to fall in wire hang test
• normal coordination in rotarod test
• normal behavior in tail suspension test
• normal behavior in social interaction test
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• lower levels of freezing in cued fear conditioning test (acoustic stimulus + foot shock)
• normal behavior in cued test 35 days after conditioning in cued fear conditioning test (acoustic stimulus + foot shock)
• normal behavior in cued fear extinction test
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• increased correct choice in spontaneous alternation and left-right discrimination T-maze tests
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• reduced time spent in center in open field test
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• significantly reduced acoustic startle reflex
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• in open field test
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• reduced locomotor activity: decrease in total distance traveled in light and dark chambers and decrease in number of transitions in light/dark transition test
• reduced locomotor activity: decrease in total distance traveled in open field test
• lower locomotor activity in home cage social activity test
• normal time spent in light chamber and normal latency to first transition
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• reduced stereotypic counts in open field test
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• less time spent apart in home cage social activity test
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• more time spent with cage with unfamiliar mouse than with empty cage in sociability test
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• less time spent with novel mouse in social novelty preference test: equal time spent with familiar and unfamiliar mouse
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growth/size/body
homeostasis/metabolism
| N |
• normal body temperature
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integument
| N |
• normal fur and whiskers
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nervous system
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• in acoustic startle reflex test
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