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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dsc2tm1.1Leu
targeted mutation 1.1, Rudolf E Leube
MGI:6509038
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Dsc2tm1.1Leu/Dsc2tm1.1Leu
Tg(Vil1-cre)20Syr/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 MGI:6693361


Genotype
MGI:6693361
cn1
Allelic
Composition
Dsc2tm1.1Leu/Dsc2tm1.1Leu
Tg(Vil1-cre)20Syr/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dsc2tm1.1Leu mutation (0 available); any Dsc2 mutation (80 available)
Tg(Vil1-cre)20Syr mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
N
• normal intestinal histology
• normal desmosomal plaques in intestines
• normal intestinal permeability
• normal susceptibility to dextran sodium sulfate (DSS)-induced colitis

growth/size/body
N
• no gross abnormalities

immune system
N
• normal susceptibility to dextran sodium sulfate (DSS)-induced colitis





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory