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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppil1em2Jgg
endonuclease-mediated mutation 2, Joseph Gleeson
MGI:6509458
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ppil1em2Jgg/Ppil1em2Jgg C57BL/6-Ppil1em2Jgg MGI:6509633
ht2
 		Ppil1em2Jgg/Ppil1em3Jgg C57BL/6-Ppil1em2Jgg Ppil1em3Jgg MGI:6509648


Genotype
MGI:6509633
hm1
Allelic
Composition		 Ppil1em2Jgg/Ppil1em2Jgg
Genetic
Background		 C57BL/6-Ppil1em2Jgg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppil1em2Jgg mutation (0 available); any Ppil1 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:300487 )
• partially resorbed embryos at E9.5, no viable embryos past E12.5




Genotype
MGI:6509648
ht2
Allelic
Composition		 Ppil1em2Jgg/Ppil1em3Jgg
Genetic
Background		 C57BL/6-Ppil1em2Jgg Ppil1em3Jgg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppil1em2Jgg mutation (0 available); any Ppil1 mutation (40 available)
Ppil1em3Jgg mutation (0 available); any Ppil1 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
decreased embryo size ( J:300487 )
• small and severely malformed embryos at E18.5

growth/size/body
decreased embryo size ( J:300487 )
• small and severely malformed embryos at E18.5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory