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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pabpn1lem1Hyfn
endonuclease-mediated mutation 1, Heng-Yu Fan
MGI:6509577
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Pabpn1lem1Hyfn/Pabpn1lem1Hyfn C57BL/6-Pabpn1lem1Hyfn MGI:6693343


Genotype
MGI:6693343
hm1
Allelic
Composition
Pabpn1lem1Hyfn/Pabpn1lem1Hyfn
Genetic
Background
C57BL/6-Pabpn1lem1Hyfn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pabpn1lem1Hyfn mutation (0 available); any Pabpn1l mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• male mice exhibit normal fertility
• increased maternal RNA in oocytes
• despite normal MII oocyte numbers

cellular
• increased maternal RNA in oocytes
• regardless of embryo genotype, zygotes arrest at 1- to 2-cell stage and fail to develop further





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory