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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(n-TRtct2)557Slac
transgene insertion 557, Susan L Ackerman
MGI:6510836
Summary 2 genotypes


Genotype
MGI:6511088
cx1
Allelic
Composition		 Gtpbp2nmf205/Gtpbp2nmf205
n-TRtct5m1J/n-TRtct5m1J
Tg(n-TRtct2)557Slac/0
Genetic
Background		 C57BL/6J-Gtpbp2nmf205 Tg(n-TRtct2)557Slac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gtpbp2nmf205 mutation (1 available); any Gtpbp2 mutation (38 available)
n-TRtct5m1J mutation (4 available); any n-TRtct5 mutation (4 available)
Tg(n-TRtct2)557Slac mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:297745 )
N
• no neurodegeneration in brain




Genotype
MGI:6511081
cx2
Allelic
Composition		 n-TRtct5m1J/n-TRtct5m1J
Tg(n-TRtct2)557Slac/0
Genetic
Background		 C57BL/6J-Tg(n-TRtct2)557Slac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
n-TRtct5m1J mutation (4 available); any n-TRtct5 mutation (4 available)
Tg(n-TRtct2)557Slac mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:297745 )
• normal seizure threshold when treated with pentylenetetrazole (PTZ) [i.e. lower threshold than non-transgenic B6J mice, which carry the n-TRtct5m1J allele]




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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory