Phenotypes associated with this allele

• Allele Symbol: Silc1^em1Uli
• Allele Name: endonuclease-mediated mutation 1, Igor Ulitsky
• Allele ID: MGI:6511794
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Silc1^em1Uli/Silc1^em1Uli	involves: C57BL/6	MGI:6511800

Genotype
MGI:6511800

hm1

• Allelic Composition: Silc1^em1Uli/Silc1^em1Uli
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal response to injury ( J:268832 )

• gait analysis indicates slower recovery from sciatic nerve injury, with homozygous mice failing to make use of the injured limb at 5 days post injury unlike wild-type controls and reaching an asymptote of recovery at 11 days post injury compared to 5 days in wild-type mice

• branch length at 2 and 3 mm proximal to the injury site is reduced in homozygous mice compared to wild-type mice at 7 days post injury

nervous system

abnormal axon extension ( J:268832 )

• reduced outgrowth in cultured dorsal root ganglion cells following replating

cellular

abnormal axon extension ( J:268832 )

• reduced outgrowth in cultured dorsal root ganglion cells following replating