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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pls3em2Bult
endonuclease-mediated mutation 2, Carol Bult
MGI:6513056
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pls3em2Bult/Pls3em2Bult C57BL/6J-Pls3em2Bult/BultJ MGI:7545089
ot2
 		Pls3em2Bult/Y C57BL/6J-Pls3em2Bult/BultJ MGI:7616744


Genotype
MGI:7545089
hm1
Allelic
Composition		 Pls3em2Bult/Pls3em2Bult
Genetic
Background		 C57BL/6J-Pls3em2Bult/BultJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pls3em2Bult mutation (1 available); any Pls3 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
decreased bone mineral density ( J:341714 )
• decreased bone mineral density at 3 months of age

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
osteoporosis DOID:11476 OMIM:166710
 J:341714




Genotype
MGI:7616744
ot2
Allelic
Composition		 Pls3em2Bult/Y
Genetic
Background		 C57BL/6J-Pls3em2Bult/BultJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pls3em2Bult mutation (1 available); any Pls3 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
decreased bone mineral density ( J:341714 )
• decreased bone mineral density at 3 months of age

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
osteoporosis DOID:11476 OMIM:166710
 J:341714




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory