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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfp998em1Aiwsk
endonuclease-mediated mutation 1, Akiko Iwasaki
MGI:6513187
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Del(13Zfp997-Vmn2r-ps103)1Aiwsk/Del(13Zfp997-Vmn2r-ps103)1Aiwsk
Zfp998em1Aiwsk/Zfp998em1Aiwsk 		involves: C57BL/6J MGI:6513224
cx2
 		Zfp998em1Aiwsk/Del(13Zfp997-Vmn2r-ps103)1Aiwsk involves: C57BL/6J MGI:6513227


Genotype
MGI:6513224
cx1
Allelic
Composition		 Del(13Zfp997-Vmn2r-ps103)1Aiwsk/Del(13Zfp997-Vmn2r-ps103)1Aiwsk
Zfp998em1Aiwsk/Zfp998em1Aiwsk
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(13Zfp997-Vmn2r-ps103)1Aiwsk mutation (0 available); any Del(13Zfp997-Vmn2r-ps103)1Aiwsk mutation (0 available)
Zfp998em1Aiwsk mutation (0 available); any Zfp998 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal DNA-templated transcription ( J:282526 )
• lack of transcriptional repression of non-ecotropic endogenous retroviruses (NEERVs)
abnormal epigenetic regulation of gene expression ( J:282526 )
• lack of transcriptional repression of non-ecotropic endogenous retroviruses (NEERVs)




Genotype
MGI:6513227
cx2
Allelic
Composition		 Zfp998em1Aiwsk/Del(13Zfp997-Vmn2r-ps103)1Aiwsk
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(13Zfp997-Vmn2r-ps103)1Aiwsk mutation (0 available); any Del(13Zfp997-Vmn2r-ps103)1Aiwsk mutation (0 available)
Zfp998em1Aiwsk mutation (0 available); any Zfp998 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
cellular phenotype ( J:282526 )
N
• normal transcriptional repression of non-ecotropic endogenous retroviruses (NEERVs)
abnormal epigenetic regulation of gene expression ( J:282526 )
• lack of transcriptional repression of non-ecotropic endogenous retroviruses (NEERVs)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory