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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nlrp9cem4Okkm
endonuclease-mediated mutation 4, Tohru Kimura
MGI:6514384
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Nlrp9aem3Okkm/Nlrp9aem3Okkm
Nlrp9bem3Okkm/Nlrp9bem3Okkm
Nlrp9cem2Okkm/Nlrp9cem4Okkm
involves: ICR MGI:6514799


Genotype
MGI:6514799
cx1
Allelic
Composition
Nlrp9aem3Okkm/Nlrp9aem3Okkm
Nlrp9bem3Okkm/Nlrp9bem3Okkm
Nlrp9cem2Okkm/Nlrp9cem4Okkm
Genetic
Background
involves: ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrp9aem3Okkm mutation (0 available); any Nlrp9a mutation (71 available)
Nlrp9bem3Okkm mutation (0 available); any Nlrp9b mutation (51 available)
Nlrp9cem2Okkm mutation (0 available); any Nlrp9c mutation (67 available)
Nlrp9cem4Okkm mutation (0 available); any Nlrp9c mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• some mice degenerate prior to implantation

reproductive system
• in female mice crossed with wild-type male mice in addition to more litters with seven or fewer pups compared with wild-type mice
• however, mice have comparable number of deliveries and normal fertilization rates

embryo
• smaller blastocysts in zygotes that form a blastocyst at E3.5 and E4.5
• fewer E3.5 mice zygotes develop a blastocyst remaining as morulae or embryos degenerate
• blocked at the 2-cell stage with asymmetric cell division
• some zygotes do not develop a blastocyst until E4.5

growth/size/body
• some zygotes do not develop a blastocyst until E4.5





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory