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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Phf7em2Osb
endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
MGI:6690454
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Phf7em2Osb/Phf7em2Osb
Tg(CAG-EGFP,Acr-EGFP)2Osb/0 		involves: 129S2/SvPas * C57BL/6NSlc MGI:6690604


Genotype
MGI:6690604
cx1
Allelic
Composition		 Phf7em2Osb/Phf7em2Osb
Tg(CAG-EGFP,Acr-EGFP)2Osb/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6NSlc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Phf7em2Osb mutation (0 available); any Phf7 mutation (27 available)
Tg(CAG-EGFP,Acr-EGFP)2Osb mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal sperm nucleus morphology ( J:298823 )
• defective histone to protamine exchange during spermiogenesis
decreased fertilization frequency ( J:298823 )
• during in vitro fertilization

cellular
abnormal sperm nucleus morphology ( J:298823 )
• defective histone to protamine exchange during spermiogenesis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory