All Phenotypes Phf7<tm1c(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Phf7^{tm1c(EUCOMM)Hmgu}
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:6690457

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Phf7^{tm1c(EUCOMM)Hmgu}/Phf7^{tm1c(EUCOMM)Hmgu} Tg(Stra8-icre)1Reb/0	involves: C57BL/6N * FVB/NJ	MGI:6690603

Allelic Composition	Phf7^{tm1c(EUCOMM)Hmgu}/Phf7^{tm1c(EUCOMM)Hmgu} Tg(Stra8-icre)1Reb/0
Genetic Background	involves: C57BL/6N * FVB/NJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Phf7^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Phf7 mutation (27 available)
Tg(Stra8-icre)1Reb mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

oligozoospermia ( J:298823 )

abnormal sperm head morphology ( J:298823 )

• globular and larger head with nuclei

globozoospermia ( J:298823 )

abnormal sperm nucleus morphology ( J:298823 )

• less condensed chromatin; defective histone to protamine exchange during spermiogenesis

enlarged sperm head ( J:298823 )

asthenozoospermia ( J:298823 )

male infertility ( J:298823 )

decreased fertilization frequency ( J:298823 )

• during in vitro fertilization

cellular