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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mir195atm1Narl
targeted mutation 1, National Applied Research Laboratory
MGI:6690843
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Mir195atm1Narl/Mir195atm1Narl
Tg(Ctsk-RFP,-cre)7Narl/0 		involves: C57BL/6 MGI:6693710


Genotype
MGI:6693710
cn1
Allelic
Composition		 Mir195atm1Narl/Mir195atm1Narl
Tg(Ctsk-RFP,-cre)7Narl/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir195atm1Narl mutation (0 available); any Mir195a mutation (2 available)
Tg(Ctsk-RFP,-cre)7Narl mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
impaired blood-brain barrier function ( J:297580 )
• at 12 months of age, mice exhibit increased blood-brain barrier (BBB) permeability relative to wild-type controls, as measured by Evans blue extravasation in the whole brain

nervous system
impaired blood-brain barrier function ( J:297580 )
• at 12 months of age, mice exhibit increased blood-brain barrier (BBB) permeability relative to wild-type controls, as measured by Evans blue extravasation in the whole brain




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory