cardiovascular system
• no gross abnormalities in cardiac morphology or function
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growth/size/body
• healthy, without gross abnormalities
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mortality/aging
• viable
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• increased cardiac hypertrophy and greater increase in heart weight to body weight (HW/BW) and tibia length (HW/TL) and lung weight to body weight (LW/BW) ratios and cardiomyocyte cross-sectional area 4 weeks after aortic banding
• increased extent of cardiac interstitial and perivascular fibrosis 4 weeks after aortic banding
• more cardiac ventricular dilation (increased left ventricle end-systolic and end-diastolic dimension) and greater decrease of fractional shortening 4 weeks after aortic banding
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reproductive system
• fertile
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