Phenotypes associated with this allele

• Allele Symbol: Gm41610^em1Scrp
• Allele Name: endonuclease-mediated mutation 1, Susan Carpenter
• Allele ID: MGI:6693618
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gm41610^em1Scrp/Gm41610^em1Scrp	C57BL/6-Gm41610^em1Scrp	MGI:6693620

Genotype
MGI:6693620

hm1

• Allelic Composition: Gm41610^em1Scrp/Gm41610^em1Scrp
• Genetic Background: C57BL/6-Gm41610^em1Scrp

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:302605 )

N • bone marrow-derived macrophages exhibit normal phagocytosis

increased circulating interleukin-13 level ( J:302605 )

• at baseline

increased circulating interleukin-5 level ( J:302605 )

• at baseline

decreased susceptibility to endotoxin shock ( J:302605 )

• LPS-treated mice exhibit 100% survival unlike wild-type mice

homeostasis/metabolism

increased circulating interleukin-13 level ( J:302605 )

• at baseline

increased circulating interleukin-5 level ( J:302605 )

• at baseline

decreased partial thromboplastin time ( J:302605 )