Phenotypes associated with this allele

• Allele Symbol: Sun3^em1Qsh
• Allele Name: endonuclease-mediated mutation 1, Qinghua Shi
• Allele ID: MGI:6693648
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sun3^em1Qsh/Sun3^em1Qsh	Not Specified	MGI:6693649

Genotype
MGI:6693649

hm1

• Allelic Composition: Sun3^em1Qsh/Sun3^em1Qsh
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:298937 )

♀N • female mice are fertile

abnormal sperm midpiece morphology ( J:298937 )

♂ • irregular caliber, bending, coiling, and/or cracking

oligozoospermia ( J:298937 )

♂ • sharp decline in epididymal sperm numbers

globozoospermia ( J:298937 )

♂ • smaller and round-headed spermatozoa with missing, mislocalized, or fragmented acrosomes despite normal chromatin condensation

abnormal manchette morphology ( J:298937 )

♂

increased male germ cell apoptosis ( J:298937 )

♂

small testis ( J:298937 )

♂

male infertility ( J:298937 )

♂

endocrine/exocrine glands

small testis ( J:298937 )

♂

cellular

abnormal sperm midpiece morphology ( J:298937 )

♂ • irregular caliber, bending, coiling, and/or cracking

oligozoospermia ( J:298937 )

♂ • sharp decline in epididymal sperm numbers

globozoospermia ( J:298937 )

♂ • smaller and round-headed spermatozoa with missing, mislocalized, or fragmented acrosomes despite normal chromatin condensation

abnormal manchette morphology ( J:298937 )

♂

increased male germ cell apoptosis ( J:298937 )

♂