About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ces5aem1Zuk
endonuclease-mediated mutation 1, Martin M Matzuk
MGI:6693654
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ces5aem1Zuk/Ces5aem1Zuk involves: C57BL/6 * DBA/2 MGI:6693754


Genotype
MGI:6693754
hm1
Allelic
Composition
Ces5aem1Zuk/Ces5aem1Zuk
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ces5aem1Zuk mutation (0 available); any Ces5a mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• mice exhibit normal testis histology and sperm morphology
• with decreased average path velocity and progressive velocity after hyperactivation
• dilated lumen, inflammation, and abnormal epithelia
• male mice sire fewer litters and pups
• however, litter size is normal over 3 month mating period

cellular
• with decreased average path velocity and progressive velocity after hyperactivation





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory