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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ddx19bem1Chaw
endonuclease-mediated mutation 1, Changjiang Weng
MGI:6693701
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ddx19bem1Chaw/Ddx19bem1Chaw C57BL/6-Ddx19bem1Chaw MGI:6693802
ht2
 		Ddx19bem1Chaw/Ddx19b+ C57BL/6-Ddx19bem1Chaw MGI:6693805


Genotype
MGI:6693802
hm1
Allelic
Composition		 Ddx19bem1Chaw/Ddx19bem1Chaw
Genetic
Background		 C57BL/6-Ddx19bem1Chaw
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddx19bem1Chaw mutation (0 available); any Ddx19b mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6693805
ht2
Allelic
Composition		 Ddx19bem1Chaw/Ddx19b+
Genetic
Background		 C57BL/6-Ddx19bem1Chaw
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddx19bem1Chaw mutation (0 available); any Ddx19b mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased interferon-alpha secretion ( J:289833 )
• by macrophages incubated with poly(I:C) or infected with Sendai virus (SeV)
increased interferon-beta secretion ( J:289833 )
• by macrophages incubated with poly(I:C) or infected with Sendai virus (SeV)

growth/size/body
growth/size/body region phenotype ( J:289833 )
• no gross abnormalities

mortality/aging
mortality/aging ( J:289833 )
• viable

reproductive system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory