About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mir455em1Zhizh
endonuclease-mediated mutation 1, Zhiqi Zhang
MGI:6694021
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mir455em1Zhizh/Mir455em1Zhizh involves: C57BL/6 MGI:6694050
hm2
 		Mir455em1Zhizh/Mir455em1Zhizh Not Specified MGI:6694028


Genotype
MGI:6694050
hm1
Allelic
Composition		 Mir455em1Zhizh/Mir455em1Zhizh
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir455em1Zhizh mutation (0 available); any Mir455 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal cartilage morphology ( J:289776 )
• increased degeneration of articular cartilage in knee at age 10 and 12 months




Genotype
MGI:6694028
hm2
Allelic
Composition		 Mir455em1Zhizh/Mir455em1Zhizh
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir455em1Zhizh mutation (0 available); any Mir455 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal cartilage morphology ( J:294778 )
• increased degeneration of articular cartilage in femoral head at age 6 months
abnormal chondrocyte morphology ( J:294778 )
• increased number of hypertrophic chondrocytes in articular cartilage in femoral head at age 6 months




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory