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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Del(7Pira1-Lilra6)1Fgla
deletion, Chr 7, Fadi G Lakkis 1
MGI:6694109
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Del(7Pira1-Lilra6)1Fgla/Del(7Pira1-Lilra6)1Fgla involves: C57BL/6 MGI:6694870
cx2
 		Del(7Pira1-Lilra6)1Fgla/Del(7Pira1-Lilra6)1Fgla
Il2rgtm1Wjl/Il2rgtm1Wjl
Rag2tm1Fwa/Rag2tm1Fwa 		involves: C57BL/6J * C57BL/6NTac MGI:6694871


Genotype
MGI:6694870
hm1
Allelic
Composition		 Del(7Pira1-Lilra6)1Fgla/Del(7Pira1-Lilra6)1Fgla
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to graft versus host disease ( J:290663 )
• no acute rejection and decreased chronic rejection score after BALB/c kidney transplantation




Genotype
MGI:6694871
cx2
Allelic
Composition		 Del(7Pira1-Lilra6)1Fgla/Del(7Pira1-Lilra6)1Fgla
Il2rgtm1Wjl/Il2rgtm1Wjl
Rag2tm1Fwa/Rag2tm1Fwa
Genetic
Background		 involves: C57BL/6J * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7Pira1-Lilra6)1Fgla mutation (0 available); any Del(7Pira1-Lilra6)1Fgla mutation (0 available)
Il2rgtm1Wjl mutation (83 available); any Il2rg mutation (176 available)
Rag2tm1Fwa mutation (45 available); any Rag2 mutation (119 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal response to transplant ( J:290663 )
• no monocyte memory response to BALB/c allograft 7 or 28 days after priming with irradiated BALB/c splenocytes
• normal primary response (primary dendritic cell and macrophage functions) to BALB/c allograft after priming with irradiated BALB/c splenocytes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory