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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ggnbp1em1Lchao
endonuclease-mediated mutation 1, Chao Lui
MGI:6695979
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ggnbp1em1Lchao/Ggnbp1em1Lchao Not Specified MGI:6695983


Genotype
MGI:6695983
hm1
Allelic
Composition
Ggnbp1em1Lchao/Ggnbp1em1Lchao
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ggnbp1em1Lchao mutation (0 available); any Ggnbp1 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• head deformities, tail bending, or the detachment of head and tail in some mice
• in mice exposed to BPA
• in some mice
• irregular heads in the sperm of some mice
• in some mice
• in mice exposed to BPA
• disorganized with large vacuoles and disorganized germ cells in some mice
• perturbed acrosome morphology and spermatid nuclei at later steps of spermatids in some mice
• however, meiosis is normal
• in some mice
• however, some mice exhibit normal fertility

homeostasis/metabolism
• mice exposed to BPA exhibit increased teratozoospermia and asthenozoospermia compared with wild-type mice

endocrine/exocrine glands
• disorganized with large vacuoles and disorganized germ cells in some mice

cellular
• head deformities, tail bending, or the detachment of head and tail in some mice
• in mice exposed to BPA
• in some mice
• irregular heads in the sperm of some mice
• in some mice
• in mice exposed to BPA





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory