About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Spata3em1Sbbx
endonuclease-mediated mutation 1, Sandrine Barbaux
MGI:6711592
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Spata3em1Sbbx/Spata3em1Sbbx C57BL/6J-Spata3em1Sbbx MGI:6711594


Genotype
MGI:6711594
hm1
Allelic
Composition		 Spata3em1Sbbx/Spata3em1Sbbx
Genetic
Background		 C57BL/6J-Spata3em1Sbbx
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spata3em1Sbbx mutation (0 available); any Spata3 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:305339 )
N
• mice exhibit normal in vivo fertility
teratozoospermia ( J:305339 )
• in some sperm with partially or completely detached acrosomes increased sperm with lipid droplets
detached acrosome ( J:305339 )
• in some sperm
impaired fertilization ( J:305339 )
• however, in vivo fertilization is normal
• sperm exhibit impaired in vitro fertilization of intake and zona-free oocytes compared with wild-type mice

cellular
teratozoospermia ( J:305339 )
• in some sperm with partially or completely detached acrosomes increased sperm with lipid droplets
detached acrosome ( J:305339 )
• in some sperm




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory