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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Spata3em1Sbbx
endonuclease-mediated mutation 1, Sandrine Barbaux
MGI:6711592
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Spata3em1Sbbx/Spata3em1Sbbx C57BL/6J-Spata3em1Sbbx MGI:6711594


Genotype
MGI:6711594
hm1
Allelic
Composition		 Spata3em1Sbbx/Spata3em1Sbbx
Genetic
Background		 C57BL/6J-Spata3em1Sbbx
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spata3em1Sbbx mutation (0 available); any Spata3 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:305339 )
N
• mice exhibit normal in vivo fertility
teratozoospermia ( J:305339 )
• in some sperm with partially or completely detached acrosomes increased sperm with lipid droplets
detached acrosome ( J:305339 )
• in some sperm
impaired fertilization ( J:305339 )
• sperm exhibit impaired in vitro fertilization of intake and zona-free oocytes compared with wild-type mice
• however, in vivo fertilization is normal

cellular
teratozoospermia ( J:305339 )
• in some sperm with partially or completely detached acrosomes increased sperm with lipid droplets
detached acrosome ( J:305339 )
• in some sperm




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory