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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccr1l1em2Semp
endonuclease-mediated mutation 2, Sergio M Pontejo
MGI:6714048
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ccr1l1em2Semp/Ccr1l1em2Semp C57BL/6NTac-Ccr1l1em2Semp MGI:6715150


Genotype
MGI:6715150
hm1
Allelic
Composition		 Ccr1l1em2Semp/Ccr1l1em2Semp
Genetic
Background		 C57BL/6NTac-Ccr1l1em2Semp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccr1l1em2Semp mutation (0 available); any Ccr1l1 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:304824 )
• normal development of bone marrow derived eosinophils (BMDEs)
• normal tissue eosinophil morphology
• normal immune cell populations
• normal calcium response of bone marrow derived eosinophils (BMDEs) after stimulation with Ccl3, Ccl11 or one of 18 other chemokines (covering at least one ligand for each known chemokine receptor)
• normal chemotaxis response of bone marrow derived eosinophils (BMDEs) towards Ccl3 or Ccl11




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory