All Phenotypes Hmcn1<tm1Vog> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hmcn1^tm1Vog
targeted mutation 1, Bruce E Vogel
MGI:6715212

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hmcn1^tm1Vog/Hmcn1^tm1Vog	involves: 129S/SvEv * C57BL/6	MGI:6715213

Allelic Composition	Hmcn1^tm1Vog/Hmcn1^tm1Vog
Genetic Background	involves: 129S/SvEv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmcn1^tm1Vog mutation (0 available); any Hmcn1 mutation (344 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryo

failure of zygotic cell division ( J:305110 )

• arrest at the 1 to 4 cell stage with multinucleate cells that often have internal polar bodies and plasma membranes with multiple invaginations

• cleavage furrows form but fail to ingress and often retract

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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