Phenotypes associated with this allele

• Allele Symbol: Fbxo10^em1Ccg
• Allele Name: endonuclease-mediated mutation 1, Christopher C Goodnow
• Allele ID: MGI:6721013
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxo10^em1Ccg/Fbxo10^em1Ccg	C57BL/6J-Fbxo10^em1Ccg	MGI:6721036

Genotype
MGI:6721036

hm1

• Allelic Composition: Fbxo10^em1Ccg/Fbxo10^em1Ccg
• Genetic Background: C57BL/6J-Fbxo10^em1Ccg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:307413 )

• adults up to 50 weeks of age appear normal, healthy and have no differences in body weight, mice show no detectable defect in B cells in bone marrow or spleen, no effect on lymph node or spleen cellularity, no effect on the magnitude or quality of a polyclonal germ cell B cell response to sheep red blood cell immunization, no effect on T cell thymic development or T cell splenic maturation, and no effect on the distribution of murine lymphoid and myeloid leukocyte subsets in the bone marrow or spleen