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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ndufa4l2tm1.2Jlob
targeted mutation 1.2, Jose Lopez-Barneo
MGI:6724161
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ndufa4l2tm1.1Jlob/Ndufa4l2tm1.2Jlob
Thtm1(cre)Te/Th+ 		involves: 129S/Sv * 129X1/SvJ * C57BL/6NCrl * C57BL/6NTac MGI:6724163


Genotype
MGI:6724163
cn1
Allelic
Composition		 Ndufa4l2tm1.1Jlob/Ndufa4l2tm1.2Jlob
Thtm1(cre)Te/Th+
Genetic
Background		 involves: 129S/Sv * 129X1/SvJ * C57BL/6NCrl * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndufa4l2tm1.1Jlob mutation (0 available); any Ndufa4l2 mutation (9 available)
Ndufa4l2tm1.2Jlob mutation (0 available); any Ndufa4l2 mutation (9 available)
Thtm1(cre)Te mutation (1 available); any Th mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal physiological response to hypoxia ( J:302384 )
• slightly higher responsiveness to hypoxia
• however, mice exhibit normal ventilatory responses to hypoxia and hypercapnia




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory