Analysis Tools
mortality/aging
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• 43 of 60 mice die within 6 weeks of birth
• however, 15 of 60 mice live longer than 8 weeks of age
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• 43 of 60 mice die within 6 weeks of birth
• however, 15 of 60 mice live longer than 8 weeks of age
|
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• fewer than expected mice are born
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reproductive system
| N |
• female mice exhibit normal fertility
• male mice exhibit normal testis size and weight
|
 |
• abnormal head shaping and flagellum biogenesis
|
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• absent in step 2-3 spermatids
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• lack of spermatozoa or only a few spermatozoa in the epididymal lumen
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• abnormally elongated and constructed sperm head shapes
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• abnormally long manchettes
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growth/size/body
|
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• in male mice
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• situs inversus abdominalis in 8 of 25 mice
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• in 12 of 25 mice
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nervous system
hydrocephaly
(
J:307591
)
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• in 8 of 25 mice
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cellular
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• absent in step 2-3 spermatids
|
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• lack of spermatozoa or only a few spermatozoa in the epididymal lumen
|
|
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• abnormally elongated and constructed sperm head shapes
|
|
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• abnormally long manchettes
|
