Phenotypes associated with this allele

• Allele Symbol: Cct6b^em1Jsha
• Allele Name: endonuclease-mediated mutation 1, Jiahao Sha
• Allele ID: MGI:6724571
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cct6b^em1Jsha/Cct6b^em1Jsha	involves: C57BL/6	MGI:6724572

Genotype
MGI:6724572

hm1

• Allelic Composition: Cct6b^em1Jsha/Cct6b^em1Jsha
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

teratozoospermia ( J:307593 )

• teratospermia characterized by neck bending and cytoplasmic retention around the head of the neck

abnormal sperm flagellum morphology ( J:307593 )

• curling of the flagellar tail is seen in the retained cytoplasm around the head of the sperm

decreased sperm progressive motility ( J:307593 )

• sperm exhibit decreased progressive motility

• however, males exhibit normal fertility, show normal testes and epididymis size, and normal spermatogenesis, with normal numbers of spermatocytes, round spermatids, and elongated spermatids per tubule, normal spermatogonia self-renewal, meiotic progression, and acrosome formation

cellular

teratozoospermia ( J:307593 )

• teratospermia characterized by neck bending and cytoplasmic retention around the head of the neck

abnormal sperm flagellum morphology ( J:307593 )

• curling of the flagellar tail is seen in the retained cytoplasm around the head of the sperm

decreased sperm progressive motility ( J:307593 )

• sperm exhibit decreased progressive motility

• however, males exhibit normal fertility, show normal testes and epididymis size, and normal spermatogenesis, with normal numbers of spermatocytes, round spermatids, and elongated spermatids per tubule, normal spermatogonia self-renewal, meiotic progression, and acrosome formation