Phenotypes associated with this allele

• Allele Symbol: Hes7^M1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:6725087
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Hes7^M1Btlr/Hes7^+	C57BL/6J-Hes7^M1Btlr	MGI:6725725

Genotype
MGI:6725725

ht1

• Allelic Composition: Hes7^M1Btlr/Hes7⁺
• Genetic Background: C57BL/6J-Hes7^M1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

kinked tail ( J:307652 )

• in 6 of 15 mice with severe kyphoscoliosis

skeleton

abnormal vertebral column morphology ( J:307652 )

• severe deformities

kyphoscoliosis ( J:307652 )

• severe kyphoscoliosis with a sharp vertebral angulation in 15 of 21 mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
spondylocostal dysostosis		DOID:0050568	OMIM:PS277300	J:307652