Phenotypes associated with this allele

• Allele Symbol: Tg(tetO-Mir24-1)#Smoc
• Allele Name: transgene insertion, Shanghai Model Organisms Center
• Allele ID: MGI:6725805
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(tetO-Mir24-1)#Smoc/0 Tg(KRT14-rtTA)F42Efu/0	involves: FVB	MGI:6726111

Genotype
MGI:6726111

cx1

• Allelic Composition: Tg(tetO-Mir24-1)#Smoc/0; Tg(KRT14-rtTA)F42Efu/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:306624 )

• fewer than expected mice are born when pups are exposed to doxycycline from E11

integument

decreased keratinocyte proliferation ( J:306624 )

• in the interfollicular epidermis at E15 in doxycycline-treated mice from E13

abnormal hair growth ( J:306624 )

• mice fail to grow hair in response to 3% minoxidil treatment unlike wild-type mice

abnormal hair cycle anagen phase ( J:306624 )

• delayed initiation in doxycycline-treated mice

thin epidermis ( J:306624 )

• thin interfollicular epidermis in doxycycline-treated mice

abnormal skin development ( J:306624 )

• immature skin in doxycycline-treated mice

growth/size/body

decreased body size ( J:306624 )

• at P3 in doxycycline-treated mice

cellular

decreased keratinocyte proliferation ( J:306624 )

• in the interfollicular epidermis at E15 in doxycycline-treated mice from E13