All Phenotypes Wdhd1<em1Isyu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Wdhd1^em1Isyu
endonuclease-mediated mutation 1, I-Shing Yu
MGI:6726123

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Wdhd1^em1Isyu/Wdhd1^em1Isyu	Not Specified	MGI:6726131

Allelic Composition	Wdhd1^em1Isyu/Wdhd1^em1Isyu
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wdhd1^em1Isyu mutation (0 available); any Wdhd1 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• no mice are recovered at E8.5

embryo

abnormal embryo development ( J:306382 )

• at E7.5

• however, mice exhibit normal development before the blastocyst stage

decreased embryo size ( J:306382 )

• at E7.5

cellular

increased apoptosis ( J:306382 )

• at E7.5

decreased cell proliferation ( J:306382 )

• at E7.5

growth/size/body

decreased embryo size ( J:306382 )

• at E7.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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