Phenotypes associated with this allele

• Allele Symbol: Tdrp^tm1Xwa
• Allele Name: targeted mutation 1, Xuanchun Wang
• Allele ID: MGI:6730107
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tdrp^tm1Xwa/Tdrp^tm1Xwa	involves: 129 * C57BL/6	MGI:6730108

Genotype
MGI:6730108

hm1

• Allelic Composition: Tdrp^tm1Xwa/Tdrp^tm1Xwa
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:307459 )

N • males show normal fertility, testis, mature epididymal sperm, seminal vesicles, caudal epididymis, seminiferous tubules, axoneme and outer dense fibers, and sperm count

abnormal sperm head morphology ( J:307459 )

• head of sperm appears normal except for a slightly looser than the wild-type in nuclear content

abnormal sperm motility ( J:307459 )

• mice exhibit low/impaired sperm motility, showing decreased average path velocity, straight line velocity, and curvilinear velocity

decreased sperm progressive motility ( J:307459 )

• the percentage of progressive mobile sperm is slightly reduced and there is an increase in the percentage of sperm with slow velocity

cellular

abnormal sperm head morphology ( J:307459 )

• head of sperm appears normal except for a slightly looser than the wild-type in nuclear content

abnormal sperm motility ( J:307459 )

• mice exhibit low/impaired sperm motility, showing decreased average path velocity, straight line velocity, and curvilinear velocity

decreased sperm progressive motility ( J:307459 )

• the percentage of progressive mobile sperm is slightly reduced and there is an increase in the percentage of sperm with slow velocity

behavior/neurological

behavior/neurological phenotype ( J:307459 )

N • mice show no obvious behavioral abnormalities