Phenotypes associated with this allele

• Allele Symbol: Usp26^tm1Smoc
• Allele Name: targeted mutation 1, Shanghai Model Organisms Center
• Allele ID: MGI:6758249
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Usp26^tm1Smoc/Y	B6.129S6-Usp26^tm1Smoc	MGI:6758251

Genotype
MGI:6758251

ot1

• Allelic Composition: Usp26^tm1Smoc/Y
• Genetic Background: B6.129S6-Usp26^tm1Smoc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

decreased male germ cell number ( J:277424 )

♂ • reduced relative percentage of mature haploid germ cell population

abnormal testis morphology ( J:277424 )

♂ • abnormal testes and spermatogenesis after 35 dpp

abnormal seminiferous tubule morphology ( J:277424 )

♂

abnormal spermatogenesis ( J:277424 )

♂ • after 35 dpp

oligozoospermia ( J:277424 )

♂ • reduced sperm counts without a change in sperm viability and motility

reduced male fertility ( J:277424 )

♂

homeostasis/metabolism

decreased circulating testosterone level ( J:277424 )

♂

decreased circulating follicle stimulating hormone level ( J:277424 )

♂

increased circulating luteinizing hormone level ( J:277424 )

♂

endocrine/exocrine glands

abnormal testis morphology ( J:277424 )

♂ • abnormal testes and spermatogenesis after 35 dpp

abnormal seminiferous tubule morphology ( J:277424 )

♂

cellular

decreased male germ cell number ( J:277424 )

♂ • reduced relative percentage of mature haploid germ cell population

oligozoospermia ( J:277424 )

♂ • reduced sperm counts without a change in sperm viability and motility