About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ikbkbem1Smoc
endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI:6758512
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ikbkbem1Smoc/Ikbkbem1Smoc C57BL/6J-Ikbkbem1Smoc MGI:6758514


Genotype
MGI:6758514
hm1
Allelic
Composition		 Ikbkbem1Smoc/Ikbkbem1Smoc
Genetic
Background		 C57BL/6J-Ikbkbem1Smoc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ikbkbem1Smoc mutation (1 available); any Ikbkb mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:309163 )
N
• mice are fertile

immune system
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:309163 )
• slight decrease in the percentage of regulatory T cells in the thymus and spleen

embryo
embryo phenotype ( J:309163 )
N
• mice born at normal Mendelian ratios

behavior/neurological
behavior/neurological phenotype ( J:309163 )
N
• mice exhibit no behavioral abnormalities

hematopoietic system
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:309163 )
• slight decrease in the percentage of regulatory T cells in the thymus and spleen




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory