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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Trpc4apem1Cya
endonuclease-mediated mutation 1, Cyagen Biosciences
MGI:6765363
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Trpc4apem1Cya/Trpc4apem1Cya C57BL/6J-Trpc4apem1Cya/Cya MGI:6765370


Genotype
MGI:6765370
hm1
Allelic
Composition
Trpc4apem1Cya/Trpc4apem1Cya
Genetic
Background
C57BL/6J-Trpc4apem1Cya/Cya
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trpc4apem1Cya mutation (0 available); any Trpc4ap mutation (36 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in mice fed a high-fat diet compared with control mice
• in mice fed a high-fat diet, but not as severe as in control mice
• in mice fed a high-fat diet, but not as severe as in control mice
• in mice fed a high-fat diet, but not as severe as in control mice
• mice fed a high-fat diet exhibit reduced hippocampal and hypothalamic injury and inflammation compared with control mice

behavior/neurological
• mice fed a high-fat diet exhibit attenuation of impairment of spatial memory observed in control mice
• in mice fed a high-fat diet, but not as severe as in control mice

liver/biliary system

growth/size/body
• in mice fed a high-fat diet compared with control mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory