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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Actrt1em1Xwei
endonuclease-mediated mutation 1, Xiaoli Wei
MGI:6765445
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Actrt1em1Xwei/Y C57BL/6-Actrt1em1Xwei MGI:6765452


Genotype
MGI:6765452
ot1
Allelic
Composition		 Actrt1em1Xwei/Y
Genetic
Background		 C57BL/6-Actrt1em1Xwei
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Actrt1em1Xwei mutation (0 available); any Actrt1 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
absent sperm head ( J:311034 )
• about 60% of spermatozoa are headless
abnormal spermatid morphology ( J:311034 )
• head-tail coupling apparatus of sperm has significant defects
reduced male fertility ( J:311034 )
• male fertility is severely impaired

cellular
absent sperm head ( J:311034 )
• about 60% of spermatozoa are headless
abnormal spermatid morphology ( J:311034 )
• head-tail coupling apparatus of sperm has significant defects




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory