All Phenotypes Spaca4<em1Pauli> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Spaca4^em1Pauli
endonuclease-mediated mutation 1, Andrea Pauli
MGI:6766529

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Spaca4^em1Pauli/Spaca4^em2Pauli	C57BL/6J-Spaca4^em1Pauli/Spaca4^em2Pauli	MGI:6771323

Allelic Composition	Spaca4^em1Pauli/Spaca4^em2Pauli
Genetic Background	C57BL/6J-Spaca4^em1Pauli/Spaca4^em2Pauli

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spaca4^em1Pauli mutation (0 available); any Spaca4 mutation (8 available)
Spaca4^em2Pauli mutation (0 available); any Spaca4 mutation (8 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:311165 )

N	• female mice exhibit normal fertility

asthenozoospermia ( J:311165 )

• slight

decreased litter size ( J:311165 )

• male mice produce smaller litter sizes compared with wild-type mice

reduced male fertility ( J:311165 )

• male mice produce smaller litter sizes compared with wild-type mice

abnormal sperm-egg fusion ( J:311165 )

• impaired sperm to egg binding

decreased fertilization frequency ( J:311165 )

• of sperm

cellular

asthenozoospermia ( J:311165 )

• slight

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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